| Player | Position | Level | School | BA Rank | MLB.com Rank | Law Rank |
| Albert Almora | OF | Prep | Mater Academy | 7 | 10 | 7 |
| Mark Appel | RHP | NCAA | Stanford | 4 | 2 | 6 |
| Chris Beck | RHP | NCAA | Georgia Southern | 80 | 25 | 70 |
| Byron Buxton | OF | Prep | Appling County | 1 | 1 | 1 |
| Gavin Cecchini | SS | Prep | Barbe | 16 | 19 | 18 |
| Carlos Correa | SS | Prep | PR Baseball Academy | 6 | 5 | 2 |
| Max Fried | LHP | Prep | Harvard-Westlake | 11 | 7 | 5 |
| Kevin Gausman | RHP | NCAA | LSU | 5 | 4 | 3 |
| Lucas Giolito | RHP | Prep | Harvard-Westlake | 9 | 8 | 9 |
| Deven Marrero | SS | NCAA | Arizona State | 14 | 13 | 13 |
| Victor Roache | OF | NCAA | Georgia Southern | 22 | 26 | 89 |
| Michael Wacha | RHP | NCAA | Texas A&M | 8 | 9 | 16 |
| Trey Williams | 3B | Prep | Valencia | 99 | 50 | 82 |
| Kyle Zimmer | RHP | NCAA | San Francisco | 3 | 6 | 8 |
| Mike Zunino | C | NCAA | Florida | 2 | 3 | 4 |